Neuroleptic malignant syndrome with normal creatine kinase.
نویسندگان
چکیده
منابع مشابه
All elevated creatine kinase is not neuroleptic malignant syndrome.
Creatine kinase (CK) is an enzyme that is found widely in muscle tissues. Raised levels would occur when there is muscle damage. Raised levels are used as one of the diagnostic criteria for Neuroleptic Malignant Syndrome (NMS). This study looks at CK levels in 30 psychotic inpatients without NMS and compares them with 10 patients with NMS. It was found that 67% of the patients without NMS had r...
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Neuroleptic malignant syndrome (NMS) is a rare but life-threatening idiosyncratic side effect resulting from neuroleptic drugs. NMS mainly occurs in patients treated with high-potency typical antipsychotics, but rarely caused by atypical antipsychotics. Although NMS is less common with atypical antipsychotic, but it seems that its incidence is rising due to increased administration of such drug...
متن کاملNeuroleptic malignant syndrome with slight elevation of creatine kinase in serum: a brief review.
Neuroleptic malignant syndrome (NMS) is the most severe adverse effect that can be caused by antipsychotics. It is an acute potentially fetal and idiosyncratic reaction that may be produced with any medication affecting the central dopaminergic system with an estimated frequency of 0.51% of the neuroleptic-treated patients.1 Its four main clinical manifestations are hyperthermia, severe muscle ...
متن کاملA rare case of neuroleptic malignant syndrome without elevated serum creatine kinase
Neuroleptic malignant syndrome (NMS) is a life-threatening adverse reaction to antipsychotic drugs. Although there is no specific examination able to diagnose NMS, serum creatine kinase (CK) elevation has been reported in over 90% of NMS patients. In this report, we describe a patient who developed NMS but had normal CK levels. The patient presented with hyperthermia of over 38°C, severe muscle...
متن کاملNeuroleptic malignant syndrome.
The neuroleptic malignant syndrome is an uncommon, severe illness that consists of fever, muscular rigidity, and stupor. Various neuroleptics have been associated with the disease. A detailed neurological, medical, and neuropathological evaluation of this case was performed. Presumably, the syndrome is secondary to biochemical dysfunction of the basal ganglia and possible of the hypothalmus.
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1996
ISSN: 0032-5473
DOI: 10.1136/pgmj.72.845.187